Dead Cells – New Game Routing

Guide for Dead Cells – New Game Routing

Notes

• This Routing includes maps from all DLCs. 
 
• I slightly shortened the map names, but they should all be identifiable. 
 
• The Runes that you can collect during your runs on a specific map are listed in (brackets) behind the map names. 
The 4 Core Runes open new ways for you on consecutive runs. 
After collecting one of the 4 core ability runes it is technically safe to die, because these ability runes will open new paths on other maps that require you to start over anyway. 
 
The Core Ability Runes you want to obtain (in this order) to be able to access most maps are: 

• Vine Rune 
• Teleportation Rune 
• Ram Rune 
• Spider Rune

 
 
Other Runes are: 

• Custom Rune 
• Challenge Rune

which are less important early on 

• Explorer Rune

which is very helpful, so try to get it early as well 

• Homunculus Rune

which is obtained automatically after beating the game once 
 

New Game – Optimal Routing

If you die before obtaining the next Ability Rune, you have to re-do the respective Route (1-4) until the Rune is obtained. Run 5 is the final full run. 
 

— 1st Run —

 
1. Quarters 
2. Promenade (Vine Rune) (Safe to die and restart now) 
 
optional: 
3. Ramparts (Custom Rune) 
4. Bridge [Boss] (Challenge Rune) 
5. Village 
6. Clock Tower 
7. Clock [Boss] 
8. Castle 
 

— 2nd Run —

 
1. Quarters 
2. Toxic Sewers (Teleport Rune) (Safe to die and restart now) 
 
optional: 
3. Ramparts 
4. Bridge [Boss] 
5. Village 
6. Forgotten Sep. (Explorer Rune) 
7. Clock [Boss] 
8. Castle 
 

— 3rd Run —

 
1. Quarters 
2. Promenade 
3. Ossuary (Ram Rune) (Safe to die and restart now) 
 
optional: 
4. Bridge [Boss] 
5. Village 
• 6. Clock Tower <or> 6. Forgotten Sep. (Explorer Rune [if not already obtained]) 
7. Clock [Boss] 
8. Castle 
 

— 4th Run —

 
1. Quarters 
2. Tox. Sewers 
3. Ancient Sewers 
4. Crypt [Boss] 
5. Sanctuary (Spider Rune) (Safe to die and restart now) 
 
optional: 
6. Forgotten (Explorer Rune [if not already obtained]) 
7. Clock [Boss] 
8. Castle 
 

— 5th Run | First Full Run —

 
1. Quarters 
2. Arboretum 
2. (optional) Prison 
• 3. Morass <or> 3. Ossuary 
• 4. Nest [Boss] [from Morass] <or> 4. Bridge [Boss] [from Ossuary] 
• 5. Village <or> 5. Shrines 
6. Clock Tower 
7. Clock [Boss] 
• 8. Castle <or> 8. Distillery 
9. Throne [Boss] (Homunculus Rune) 
 

— After beating the Hand —

 
1. Quarters (Cavern Key) 
2. Tox. Sewers 
2. (optional) Corrupted Prison 
3. Ancient Sewers 
4. Crypt [Boss] 
5. Graveyard 
6. Cavern 
7. Haven [Boss] 
 
optional: 
• 8. Castle <or> 8. Distillery 
9. Throne [Boss] 
 
————————- 
 
After all this you’re basically ready for NG+ (Boss Cell 1), 
but instead you should consider to farm more Blueprints 
and Cells, and to visit the remaining maps on BC0. 
 

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